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| 1855 |
| | Jamaican-born nurse Mary Seacole sets up her own 'British Hotel' in the Crimea to provide food and nursing for soldiers in need | |
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| 1856 |
| | The first Neanderthal man to be discovered is unearthed by quarry workers in the Neander valley, near Düsseldorf | |
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| 1856 |
| | English chemist William Henry Perkin accidentally creates the first synthetic die, aniline purple (now known as mauve) | |
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| 1857 |
| | French chemist Louis Pasteur proves the existence of micro-organisms by showing that a liquid will only ferment if exposed to contamination from the air | |
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| 1858 |
| | Charles Darwin is alarmed to receive in his morning post a paper by Alfred Russell Wallace, outlining very much his own theory of evolution | |
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| 1859 |
| | Charles Darwin puts forward the theory of evolution in On the Origin of Species, the result of 20 years' research | |
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| 1860 |
| | Florence Nightingale opens a training school for nurses in St Thomas's Hospital, establishing nursing as a profession | |
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| 1861 |
| | English chemist and physicist William Crookes isolates a new element, thallium | |
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| 1861 |
| | Hungarian physician Ignaz Philipp Semmelweis publishes his discovery that deaths from puerperal fever can be dramatically reduced by a strict hand-washing routine | |
| | The dissecting room
Wellcome Library, London
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| 1862 |
| | Louis Pasteur uses heat to destroy the micro-organisms in liquid food, in the process that becomes known as pasteurization | |
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